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A New Influenza Virus (Swine Flu)
Novel influenza A (H1N1) is a new flu virus of swine origin that was first detected in April, 2009. The virus is infecting people and is spreading from person-to-person, sparking a growing outbreak of illness in the United States. An increasing number of cases are being reported internationally as well.
It’s thought that novel influenza A (H1N1) flu spreads in the same way that regular seasonal influenza viruses spread; mainly through the coughs and sneezes of people who are sick with the virus.
It’s uncertain at this time how severe this novel H1N1 outbreak will be in terms of illness and death compared with other influenza viruses. Because this is a new virus, most people will not have immunity to it, and illness may be more severe and widespread as a result. In addition, currently there is no vaccine to protect against this novel H1N1 virus. CDC anticipates that there will be more cases, more hospitalizations and more deaths associated with this new virus in the coming days and weeks.
Novel influenza A (H1N1) activity is now being detected through CDC’s routine influenza surveillance systems and reported weekly in FluView. CDC tracks U.S. influenza activity through multiple systems across five categories. The fact that novel H1N1 activity can now be monitored through seasonal surveillance systems is an indication that there are higher levels of influenza-like illness in the United States than is normal for this time of year. About half of all influenza viruses being detected are novel H1N1 viruses.
CDC Response
CDC continues to take aggressive action to respond to the outbreak. CDC’s response goals are to reduce the spread and severity of illness, and to provide information to help health care providers, public health officials and the public address the challenges posed by this new public health threat.
CDC is issuing updated interim guidance daily in response to the rapidly evolving situation.
Clinician Guidance
CDC has issued interim guidance for clinicians on identifying and caring for patients with novel H1N1, in addition to providing interim guidance on the use of antiviral drugs. Influenza antiviral drugs are prescription medicines (pills, liquid or an inhaler) with activity against influenza viruses, including novel influenza H1N1 viruses. The priority use for influenza antiviral drugs during this outbreak is to treat severe influenza illness, including people who are hospitalized or sick people who are considered at high risk of serious influenza-related complications.
Public Guidance
In addition, CDC has provided guidance for the public on what to do if they become sick with flu-like symptoms, including infection with novel H1N1. CDC also has issued instructions on taking care of a sick person at home. Novel H1N1 infection has been reported to cause a wide range of symptoms, including fever, cough, sore throat, body aches, headache, chills and fatigue. In addition, a significant number of people also have reported nausea, vomiting or diarrhea. Everyone should take everyday preventive actions to stop the spread of germs, including frequent hand washing and people who are sick should stay home and avoid contact with others in order to limit further spread of the disease.
Testing
CDC has developed a PCR diagnostic test kit to detect this novel H1N1 virus and has now distributed test kits to all states in the U.S. and the District of Columbia and Puerto Rico. The test kits are being shipped internationally as well. This will allow states and other countries to test for this new virus. This increase in testing will likely result in an increase in the number of confirmed cases of illness reported. This, combined with ongoing monitoring through Flu View should provide a fuller picture of the burden of disease in the United States over time.
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Antiviral Drugs A H1N1 Flu (Swine Flu) - Tamiflu
Antiviral Drugs
Antiviral drugs are medicines (pills, liquid or an inhaler) with activity against influenza viruses, including swine influenza viruses. Antiviral drugs can be used to treat swine flu or to prevent infection with swine flu viruses. Influenza antiviral drugs only work against influenza viruses -- they will not help treat or prevent symptoms caused by infection from other viruses that can cause symptoms similar to the flu.
There are four influenza antiviral drugs approved for use in
the United States (Tamiflu, zanamivir, amantadine and rimantadine). The swine influenza A (H1N1) (Swine Flu) viruses that have been detected in humans in the United States and Mexico are resistant to amantadine and rimantadine so these drugs will not work against these swine influenza viruses. Laboratory testing on these swine influenza A (H1N1) (Swine Flu) viruses so far indicate that they are susceptible (sensitive) to Tamiflu and zanamivir.
Benefits of Antiviral Drugs
Treatment: If you get sick, antiviral drugs can make your illness milder and make you feel better faster. They may also prevent serious influenza complications. Influenza antiviral drugs work best when started soon after illness onset (within two 2 days), but treatment with antiviral drugs should still be considered after 48 hours of symptom onset, particularly for hospitalized patients or people at high risk for influenza-related complications.
Prevention: Influenza antiviral drugs also can be used to prevent influenza when they are given to a person who is not ill, but who has been or may be near a person with swine influenza. When used to prevent the flu, antiviral drugs are about 70% to 90% effective. When used for prevention, the number of days that they should be used will vary depending on a person’s particular situation.
CDC Recommendation
CDC recommends the use of Tamiflu (oseltamivir) or zanamivir for the treatment and/or prevention of infection with swine influenza viruses.
· Tamiflu (Oseltamivir) is approved to both treat and prevent influenza A and B virus infection in people one year of age and older.
· Zanamivir (brand name Relenza ®) is approved to treat influenza A and B virus infection in people 7 years and older and to prevent influenza A and B virus infection in people 5 years and older.
Recommendations for using antiviral drugs for treatment or prevention of swine influenza will change as we learn more about this new virus.
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World and U.S. Human Cases of H1N1 Flu Infection (Swine flu)
Novel Influenza A (H1N1) Cases.
19 May 2009, 40 countries have officially reported 9830 cases of influenza A (H1N1) infection (Swine flu), including 79 deaths.
Mexico has reported 3648 laboratory confirmed human cases of infection, including 72 deaths. The United States has reported 5469 laboratory confirmed human cases, including 6 deaths.
The following countries have reported laboratory confirmed cases with no deaths - Argentina (1), Australia (1), Austria (1), Belgium (5), Brazil (8), Canada (496), Chile (4), China, Hong Kong Special Administrative Region (7), Colombia (11), Costa Rica (9), Cuba (3), Denmark (1), Ecuador (1), El Salvador (6), Finland (2), France (14), Germany (14), Guatemala (3), India (1), Ireland (1), Israel (7), Italy (9), Japan (159), Korea (3), Malaysia (2), Netherlands (3), New Zealand (9), Norway (2), Panama (59), Peru (2), Poland (1), Portugal (1), Spain (103), Sweden (3), Switzerland (1), Thailand (2), Turkey (2) and the United Kingdom (102).
The ongoing outbreak of novel influenza A (H1N1) continues to expand in the United States. CDC expects that more cases, more hospitalizations and more deaths from this outbreak will occur over the coming days and weeks.
5469 Confirmed Cases of H1N1 Flu (Swine Flu) in 48 States (U.S.)
U.S. Human Cases of A H1N1 Flu Infection (Swine flu)
(As of May 19, 2009,)States*
Deaths
Alabama
61
Arkansas
3
Arizona
488
2
California
553
Colorado
56
Connecticut
56
Delaware
69
Florida
103
Georgia
25
Hawaii
21
Idaho
8
Illinois
707
Indiana
96
Iowa
71
Kansas
34
Kentucky**
16
Louisiana
65
Maine
10
Maryland
39
Massachusetts
156
Michigan
165
Minnesota
38
Mississippi
4
Missouri
20
Montana
9
Nebraska
28
Nevada
31
New Hampshire
20
New Jersey
18
New Mexico
68
New York
267
North Carolina
12
North Dakota
3
Ohio
13
Oklahoma
42
Oregon
94
Pennsylvania
55
Rhode Island
8
South Carolina
36
South Dakota
4
Tennessee
85
Texas
556
3
Utah
91
Vermont
1
Virginia
23
Washington
362
1
Washington, D.C.
13
Wisconsin
766
TOTAL*(48)
5,469 cases
6 deaths
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